An In Vivo Study to Evaluate and Compare the Chitosan nanoparticle solution, 2% Chlorhexidine, and Normal Saline as Root Canal Irrigants in primary teeth.

COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF CHITOSAN NANOPARTICLES, CHLORHEXIDINE AND NORMAL SALINE AGAINST E. FAECALIS AS ROOT CANAL IRRIGANTS IN PRIMARY TEETH- AN IN VIVO STUDY - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/069706

Enrollment

Registered

2024-07-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: CHITOSAN NANOPARTICLE SOLUTION AND 2% CHLORHEXIDINE: THE SAMPLES WILL BE TAKEN AT BASELINE AND AFTER IRRIGATING THE CANALS DURING PULPECTOMY THE STUDY WILL TAKE 1 MONTH Control Interven

Eligibility

Inclusion criteria

Inclusion criteria: • It will be comprised of subjects willing to participate in the study. • Presence of signs such as prolonged or spontaneous pain, pathological mobility, sensitivity to percussion. • Patients requiring endodontic treatment in primary teeth with at least two third of total root length remaining were included in the study.

Exclusion criteria

Exclusion criteria: • The medically compromised patients and patients on antibiotics within three months will be excluded from the study. • Patients who are not willing to participate

Design outcomes

Primary

Measure	Time frame
antimicrobial efficacy chitosan nanoparticle, 2% chlorhexidine and normal saline as root canal irrigantsTimepoint: AT BASELINE AND SAME DAY AFTER IRRIGATION	—

Secondary

Measure	Time frame
anitimicrobial efficacy against E. faecalisTimepoint: AT BASELINE (PRE IRRIGATION) AND SAME AFTER AFTER IRRIGATION	—

Countries

India

Contacts

Public ContactNEHA SHEORAN

PT. BD SHARMA UNIVERSITY

sheoran.neha@yahoo.co.in9711544829

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026