FindTrial
Sign In

Study of Effects of Intravenous Dexmeditomidine bolus Versus intravenous Dexmeditomidine bolus with continuous intravenous injection of lignocaine on Measurements of blood pressure, heart rate, oxygen saturation in patients undergoing Short Laparoscopic Surgeries .

Effects of Intravenous Dexmeditomidine Bolus Versus IV Dexmeditomidine Bolus with IV Lignocaine Infusion on Perioperative Hemodynamics in Patients Undergoing Short Laparoscopic Surgeries – A Randomized Controlled Trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/069701
Enrollment
50
Registered
2024-07-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.Dexmeditomidine and inj. Lignocaine group as Group DL.: Inj. Dexmedetomidine 0.6 mcg/kg IV bolus diluted to 10ml given over 10 mins & inj. IV lignocaine bolus 1.5 mg/kg diluted to

Sponsors

Vijaynagar institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing short laparoscopic surgeries and are ASA grade 1or2

Exclusion criteria

Exclusion criteria: Refusal of patient for the clinical trial Patient with history of severe hepatic, renal, cardiac and neurological disease, diabetes with autonomic dysfunction, uncontrolled hypertension, obesity body mass index more than 30kgperm2 Patient on chronic use of sedative medications Allergy to local anesthetics like lignocaine Inability to comprehend pain assessment

Design outcomes

Primary

MeasureTime frame
Changes in mean arterial pressure after 15 mins after pneumoperitoneum in short laparoscopic Surgeries.Timepoint: Above parameters recorded At following intervals– on arrival into OT [basal value], after study drug bolus, pre induction, post intubation at 1min, at every 5min and 15 mins till the initiation of pneumoperitoneum insufflation, immediate post insufflation and every 15min till the end of surgery—

Secondary

MeasureTime frame
Changes in systolic blood pressure (SBP) diastolic blood pressure (DBP) and heart rate . Duration till post-operative rescue analgesia based on NRS pain scale [0-10] . Incidence of post-operative nausea vomiting by VDS scale [0-4] . Incidence of post operative shivering. Quality of recovery after extubation by QoR40 scaleTimepoint: Pain by NRS and duration for rescue analgesia , incidence & severity of PONV by VDS , aldrete score are measured at 5 mins, 15 mins and 30 mins followed by every hour till discharge from PACU. Quality of recovery assessed by QoR40 scale over next 24 hours—

Countries

India

Contacts

Public ContactDr Anuradha H

Vijaynagar institute of medical sciences

megu.gwiz@gmail.com9632551363

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026