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Comparison of sugammadex versus neostigmine on respiratory muscle strength recovery after extubation.

Comparative Evaluation of Sugammadex Versus Neostigmine on Recovery of Respiratory Muscle Strength in the Post Extubation Period. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069683
Enrollment
60
Registered
2024-06-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H712- Cholesteatoma of mastoid Health Condition 2: H701- Chronic mastoiditis

Interventions

Intervention1: Sugammadex: I will compare the effect Sugammadex (2mg/kg) with Neostigmine (0.5 mg/kg) on resoiratory muscle strength in post extubation period and 30 minutes after shifting in PACU Co

Sponsors

ESIC Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologist (ASA) physical status 1 and 2 posted for surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Parturient or lactating women OR undergoing thoracic or abdominal surgery OR neuromuscular disease chronic obstructive pulmonary disease significant kidney and liver disease OR allergic to rocuronium neostigmine

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the effect of sugammadex and neostigmine on difference in thickening fraction of internal oblique (TFIO) from baseline to TOFR more than or equal to 0.9Timepoint: preoperative and in Post extubation at TOFR more than or equal to 0.9

Secondary

MeasureTime frame
compare change in TFIO and diaphragm excursion from baseline to 30 minutes in PACU in both groupsTimepoint: 30 minutes in PACU

Countries

India

Contacts

Public ContactDR Sonia Saini

ESIC Medical College and Hospital

rashmi.virmani@gmail.com9654959719

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026