Skip to content

Dentin bridge formation and resolution of pain comparing two different medicated agents for dental filling

Cone Beam Computed Tomographic evaluation of dentin bridge formation using Mineral Trioxide Aggregate with Melatonin and Freeze Dried Amniotic Membrane for Direct Pulp Capping in permanent Molars A Randomized Controlled Trial - NIL

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069664
Enrollment
78
Registered
2024-06-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Mineral Trioxide Aggregate(MTA) and Melatonin: Group2 : MTA with 3 mg freshly powdered Melatonin tablet mixed in a 1:1 ratio and used as a direct plulp capping agent Frequecy: one time

Sponsors

Subbaiah Institute of Dental Sciences NH Purle Shivamogga Karnataka India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with class 1 deep carious lesion in mandibular first and second molar Teeth with vital pulp, mature apex

Exclusion criteria

Exclusion criteria: Patients with habit of tobacco chewing and smoking Pregnant and lactating mothers Diabetic patients Teeth with immature apex, periapical pathosis Teeth with irreversible pulpitis

Design outcomes

Primary

MeasureTime frame
Dentin bridge formation in the compared groups evaluated with the help of intra oral periapical radiograph (IOPAR) and Cone Beam Computed Tomography (CBCT) Timepoint: Baseline response before starting the procedure, immediately after treatment, 3 months, 6months, 9months and 12 months after treatment

Secondary

MeasureTime frame
Resolution of signs and symptoms clinically and radiographically Resolution of pain assessed with help of pain scaleTimepoint: 3,6,9,12 months

Countries

India

Contacts

Public ContactDrPraveena Sharma

Subbaiah Institute of Dental Sciences

praveenasharma89@gmail.com7899862846

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026