Efficacy of noradrenaline vs dopamine in septic shock Preterm babies.: open label randomised control trial

Efficacy of noradrenaline vs dopamine in septic shock with late onset sepsis in Preterm babies.: open label randomised control trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069595

Enrollment

Registered

2024-06-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P299- Cardiovascular disorder originating in the perinatal period, unspecified Health Condition 2: P299- Cardiovascular disorder originating in the perinatal period, unspecified Health Condition 3: P299- Cardiovascular disorder originating in the perinatal period, unspecified

Interventions

Intervention1: Noradrenaline: This group will receive noradrenaline Intravenous infusion in a dose of 0.1-0.3 mcg/kg/min intravenous route Inotrope will be escalated every 30 mins till response. C

Eligibility

Inclusion criteria

Inclusion criteria: Neonates less than 37 weeks with suspected late onset sepsis.

Exclusion criteria

Exclusion criteria: 1.Congenital structural heart disease 2.Neonate who is already on inotropes before eligibility

Design outcomes

Primary

Measure	Time frame
Recovery from shock and duration of inotrope requirement . time duaration for normalisation of clinical parameters and echocardiographic parameters. Timepoint: one year	—

Secondary

Measure	Time frame
Mortality in both groupsTimepoint: one year	—

Countries

India

Contacts

Public ContactVarsha Kanhu Deodhe

Government medical college, Aurangabad.

dramolkj@yahoo.com9823900641

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026