Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Control Intervention1: NIL: NIL
Control Intervention2: NIL: NIL
Sponsors
DrJanani M G
Eligibility
Inclusion criteria
Inclusion criteria: Adult males or females with healthy periodontium and with no systemic conditions Adult males or females with a diagnosis of type 2 diabetes mellitus and periodontitis Diabetes defined as those patients diagnosed with type 2 diabetes mellitus and are on oral hypoglycemic drugs for past one year with HbA1c lesser than equal to 10% Periodontitis defined as those patients with periodontal probing pocket depth greater than or equal to 6mm,clinical attachment loss greater than or equal to 5mm,full mouth plaque score greater than 20%,full mouth bleeding score greater than 10% with radiographic evidence of bone loss extending to middle or apical third of the root with at least 20 natural teeth excluding third molars
Exclusion criteria
Exclusion criteria: Patients under immunosuppressants and or antibiotics and or anti inflammatory medications and or any drugs that could influence the periodontium for past 6 months Pregnant or lactating mothers History of current and past smokers Previous history of periodontal or orthodontic therapy Patients receiving iron replacement therapy for anemia Patients with uncontrolled diabetes mellitus with HbA1c greater than 10% Patients with a history of any other systemic disease other than type 2 diabetes mellitus and those patients under insulin therapy will be excluded Subjects not willing to participate and not willing to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating the role of hepcidin-ferroportin axis in regulating iron homeostasis in generalised stage iii/iv periodontitis with and without type 2 diabetes mellitus will further enhance our knowledge on the underlying molecular mechanisms mediating inflammation in periodontitis and in type 2 diabetes associated periodontitis Timepoint: There is no different time points in this study | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Devapriya Appukuttan
SRM Dental College, Chennai
Outcome results
None listed