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Role of 1 percent topical Spirulina gel as intervention in participants having Oral Lichen Planus

Comparative evaluation of efficacy of topical application of Spirulina gel 1 percent and triamcinolone acetonide 0.1 percent in the management of Oral Lichen Planus- A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/069548
Enrollment
50
Registered
2024-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K121- Other forms of stomatitis

Interventions

Intervention1: Topical Spirulina 1%: thrice daily for 4 weeks, after that thrice daily with 15 days follow up for 1 month Control Intervention1: Topical triamcinolone acetonide 0.1%: thrice daily for

Sponsors

Dr Nitika Aggarwal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) All clinically Diagnosed cases with atrophic, erosive, reticular or any other form of oral lichen Planus. 2) Patients above 21 years of age. 3) Patients with no contraindications or documented allergies to the medications which are being used for study. 4) Patients willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1) Previously treated patients of oral lichen planus in last 3 months or those who have left treatment in-between, or undergoing any other treatment modality. 2) Patients with co-existing systemic illness like diabetes mellitus, hypertension. 3) Pregnant and lactating mother.

Design outcomes

Primary

MeasureTime frame
Burning sensation (Visual analog scale), Size of the lesion (using vernier caliper), Clinical assessment (Thongprasom score)Timepoint: weekly for 4 weeks, after that 15 days for 1 month

Secondary

MeasureTime frame
To record the adverse reactions, if any, with both the drugs in either of the two groups, To record the recurrence of the lesion in any of the two groupsTimepoint: weekly for 4 weeks, after that 15 days for 1 month

Countries

India

Contacts

Public ContactDr Nitika Aggarwal

Government dental college and hospital, Mumbai

drvijayaomr@gmail.com9676557606

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026