Skip to content

Role of preoperative chlorhexidine mouth wash in the prevention of postoperative respiratory complications

Role of preoperative chlorhexidine mouth wash in the prevention of postoperative respiratory complications in patients with poor oral hygiene undergoing elective surgery - randomized controlled trial - nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069511
Enrollment
289
Registered
2024-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: J159- Unspecified bacterial pneumonia

Interventions

Intervention1: Mouth rinsing with chlorhexidine mouthwash: Preoperatively patient will be asked to rinse his mouth with chlorhexidine mouthwash for 5 minutes Control Intervention1: Saline mouthwash: P

Sponsors

Council for science and technology UP
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA grade I/II, with poor oral hygiene (OHI more than 6), between 18-65 years of age posted for elective abdominal surgeries of less than 4 hours duration under general anaesthesia using endotracheal tube were included in the study.

Exclusion criteria

Exclusion criteria: Patients undergoing laparoscopic surgeries, thoracic, cardiac and major bowel surgeries and patients in which supraglottic devices were used for GA were excluded from the study. Patients with active URTI/LRTI, COPD/asthma, active smokers, with alcohol abuse, diabetes mellitus, morbid obesity, any immune deficiency, heart insufficiency, those with known allergy to chlorhexidine, those on broad spectrum antibiotics and negative consent to participate in trial will also be excluded from the study. Patients who have not smoked for a year or longer will be classified as not having a smoking habit. Patients in whom prompt postoperative extubation could not be anticipated or neurological complications appeared, or those requiring re-intubation or re- exploration and those surgeries that extend beyond 4 hours will be dropped from the study.

Design outcomes

Primary

MeasureTime frame
Incidence of pneumonia in postoperative periodTimepoint: Baseline, 3 days and 7 days

Secondary

MeasureTime frame
Duration of hospital stay after surgeryTimepoint: 1 week, 2 week & 3 week

Countries

India

Contacts

Public ContactDr Shefali Gautam

KGMU

drshefaligautam@gmail.com09450610553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jul 31, 2026