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Comparison of high flow nasal cannula and standard Oxygen delivery for management of Transient Tachypnea of New born

Efficacy of high flow nasal cannula vs standard Oxygen delivery for management of Transient Tachypnea of New born- A Randomized control trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069504
Enrollment
60
Registered
2024-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P221- Transient tachypnea of newborn

Interventions

Intervention1: HFNC in TTNB: late preterm and term neonates within 6 hours of life having mild respiratory distress under suspicion og TTNB are kept on HHHFNC and compared with those kept on nasal can

Sponsors

none
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: gestational age = 34 weeks admitted within first 6 hours of life.

Exclusion criteria

Exclusion criteria: 1)Congenital anomalies incompatible with life. 2)history of thick meconium stained fluid and/or diagnosis of meconium aspiration syndrome 3)antenatal diagnosis of major congenital pulmonary or cardiac anomalies 4)initial CXR/ clinical finding demonstrating air leak 5)Downe score = 6 6)Severe Respiratory distress syndrome

Design outcomes

Primary

MeasureTime frame
1.To compare the duration of oxygen requirement between HFNC and standard oxygen therapy.Timepoint: Respiratory distress score at 6, 12 and 24 hours of starting HFNC or standard oxygen therapy.

Secondary

MeasureTime frame
1. Comparison of Respiratory distress score (Downe’s score) at 6, 12 and 24 hrs of life. 2. To compare need of advanced respiratory support (CPAP/Mechanical ventilation) in both arms. 3. Duration of NICU admission 4. Compare need of upper airway care like frequency of suctioning, nebulization, aerosol therapy in both arms. Timepoint: hospital stay in days downes score

Countries

India

Contacts

Public ContactMeghana

KALINGA INSTITUTE OF MEDICAL SCIENCES

blmeghana441@gmail.com9437084476

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026