To compare drugs having more pain relieving action by adding them to primary drug and giving via abdominal block in patients undergoing lower abdominal surgeries

A comparative study of Magnesium Sulphate versus Dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patients undergoing lower abdominal surgeries - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069447

Enrollment

Registered

2024-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R52- Pain, unspecified Health Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: A comparative study of magnesium sulphate versus dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA grade I or II fit patients, 2)Ages between 18 and 65 years, 3) Patients undergoing lower abdominal surgeries under spinal anaesthesia, 4) Hemodynamically stable patients with all routine investigations within normal limits without any other co-morbidities, 5)Patients who are not on any cardiac related drugs, 6) Availability of written informed consent from concerned patient.

Exclusion criteria

Exclusion criteria: 1)Patients not willing to participate in this study, 2)Patients with ASA physical status III and above physical status, 3)Patients less than 18 years and above 65 years of age, 4)Patients with uncontrolled systemic disorders like neurological, cardiac, metabolic, renal, pulmonary disorders, hepatic disease with coagulation abnormalities etc, 5)Patients on calcium channel blocker, 6)Patients having local infection at the site where needle for block was to be inserted, 7)Patients with contraindication for spinal anaesthesia, 8)Patients with bleeding or coagulation disorders, 9)Patients with known allergies to the study drugs, 10)Patients with weight less than 40 kgs and height less than 140 cms

Design outcomes

Primary

Measure	Time frame
A comparative study of magnesium sulphate versus dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeriesTimepoint: After administration of the block, pain scores will be assessed in both the groups in less than 5 minutes after giving block, after 2 hours, after 4 hours, after 6 hours, after 12 hours, after 16 hours, after 20 hours, and after 24 hours will be assessed	—

Measure

Time frame

A comparative study of magnesium sulphate versus dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeriesTimepoint: After administration of the block, pain scores will be assessed in both the groups in less than 5 minutes after giving block, after 2 hours, after 4 hours, after 6 hours, after 12 hours, after 16 hours, after 20 hours, and after 24 hours will be assessed

—

Secondary

Measure	Time frame
A comparative study of magnesium sulphate & dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeriesTimepoint: Duration of analgesia will be assessed post giving block after surgery & time to rescue analgesia will be assessed	—

Countries

India

Contacts

Public ContactDr Chhaya M Suryawanshi

Dr. D. Y. Patil Medical College, Hospital and Research Centre

chhayasuryawanshi@gmail.com9922888201

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026