For cesarean section height adjusted dose of bupivacaine and fixed dose of bupivacaine is used for spinal anaesthesia -which one is better for reducing incidence of hypotension

Comparison of incidence of hypotension in height adjusted dose vs fixed dose of bupivacaine in spinal anesthesia in cesarean section: A randomised controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069444

Enrollment

Registered

2024-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: Patient undergoing cesarean section receiving height adjusted dose of bupivacaine heavy for spinal anaesthesia: Comparing incidence of hypotension in height adjusted dose (0.06mg/cm) 0.

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 yrs ASA1,2 Elective cesarean section Singleton pregnancy more than 37weeks Uncomplicated pregnancy

Exclusion criteria

Exclusion criteria: Presenting with any systemic illness Emergent surgery and labouring parturients Multiple or twin pregnancy

Design outcomes

Primary

Measure	Time frame
Incidence of hypotension in height adjusted dose of 0.5% heavy bupivacaine (0.06mg/cm) in cesarean section under spinal anaesthesia compared to fixed dose 2ml(10mg) 0.5% heavy bupivacaine in cesarean section under spinal anaesthesia in control groupTimepoint: Blood pressure reading will be monitored once before spinal anaesthesia then after spinal anaesthesia every 1 min for 10 mins, every 5mins till 30 mins then every 10 mins till end of surgery.	—

Measure

Time frame

Incidence of hypotension in height adjusted dose of 0.5% heavy bupivacaine (0.06mg/cm) in cesarean section under spinal anaesthesia compared to fixed dose 2ml(10mg) 0.5% heavy bupivacaine in cesarean section under spinal anaesthesia in control groupTimepoint: Blood pressure reading will be monitored once before spinal anaesthesia then after spinal anaesthesia every 1 min for 10 mins, every 5mins till 30 mins then every 10 mins till end of surgery.

—

Secondary

Measure	Time frame
Cumulative dose of vasopressor(ephedrine) requiredTimepoint: After spinal anaesthesia till the end of surgery;Extent of surgical anaesthesia in each groupTimepoint: Time to achieve T6 level of sensory block and highest level of sensory block will be noted after administration of drug. Time to achieve bromage score 1 and time to achieve maximum level(bromage score 3) for motor block after drug administration will be noted.;Incidence of nausea and vomiting in each groupTimepoint: After spinal anaesthesia till end of surgery;Intraoperative fluid requirementTimepoint: After spinal anaesthesia till end of surgery;Other complications if anyTimepoint: After intrathecal drug administration in each group	—

Measure

Time frame

Cumulative dose of vasopressor(ephedrine) requiredTimepoint: After spinal anaesthesia till the end of surgery;Extent of surgical anaesthesia in each groupTimepoint: Time to achieve T6 level of sensory block and highest level of sensory block will be noted after administration of drug. Time to achieve bromage score 1 and time to achieve maximum level(bromage score 3) for motor block after drug administration will be noted.;Incidence of nausea and vomiting in each groupTimepoint: After spinal anaesthesia till end of surgery;Intraoperative fluid requirementTimepoint: After spinal anaesthesia till end of surgery;Other complications if anyTimepoint: After intrathecal drug administration in each group

—

Countries

India

Contacts

Public ContactDr Fateh Singh Bhati

Dr SN medical college

fatehbhati68@gmail.com9414127176

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026