To evaluate which sealer shows good healing outcome and less post operative pain.

Effect of bioceramic sealers on healing outcome and post operative pain: an in vivo study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069443

Enrollment

100

Registered

2024-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Resin based sealer: Resin based sealers is used for obturation to check the status of the healing and post operative pain Intervention2: Bio ceramic sealers: Bio ceramic sealers is used

Eligibility

Inclusion criteria

Inclusion criteria: 1.Both male and female genders. 2.Age of patient between 18-60 years. 3.Teeth with fully formed apices requiring root canal therapy. 4.Posterior teeth. 5.Horizontal supracrestal root fracture. 6.Good health(AMERICAN SOCIETY OF ANESTHESIOLOGISTS CLASSIFICATION I AND II.) 7.Presence of periapical radiolucency upto 5mm. 8.Irreversible pulpitis ( SYMPTOMATIC/ ASYMPTOMATIC) 9. Patient consenting to be part of this study.

Exclusion criteria

Exclusion criteria: 1. Use of any analgesic, anti inflammatory or antibiotics before treatment. 2. Previous endodontic intervention. 3. Evidence of vertical root fracture. 4. Non restorable teeth. 5. Patient who were unable to communicate their symptoms because of psychological disorders. 6. Tooth was affected by cracks, severe periodontal bone loss due to chronic periodontitis accompanying mobility of tooth.

Design outcomes

Primary

Measure	Time frame
1.To evaluate healing outcome of bioceramic sealer 2. to evaluate healing outcome of resin based sealer 3. to compare healing outcome of bioceramic sealer 4. to compare healing outcome of resin based sealer.Timepoint: healing will be checked at base line 3 months 6 months and 12 months interval	—

Secondary

Measure	Time frame
To evaluate and compare the intensity of pain after obturation using BC sealer and Resin based sealer.2.To evaluate and compare the intensity of pain after obturation using BC sealer and Resin based sealer. Timepoint: pain will be measured by NRS scale. observation will be done at 4hr 24hr 48hr	—

Countries

India

Contacts

Public ContactDr Rohit Kochhar

ITS dental college hospital and research centre, greater noida

hod.cons.gn@its.edu.in9810034451

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026