To compare the effects of lignocaine given as nebulization with intravenous lignocaine for decreasing of stress response to laryngoscopy and intubation in patients posted for elective general anaesthesia.

A comparative study of lignocaine nebulization with intravenous lignocaine for attenuation of pressor response to laryngoscopy and intubation - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069435

Enrollment

100

Registered

2024-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Two Different routes(Nebulization and intravenous) of Lignocaine 2% is used prior to laryngoscopy and intubation: Lignocaine 2% 2mg/kg dose is used in two different routes intravenous a

Eligibility

Inclusion criteria

Inclusion criteria: All ASA 1 and 2 patients between 18-65 years posted for elective surgeries under general anesthesia.

Exclusion criteria

Exclusion criteria: 1) ASA grade 3 and 4. 2) Diabetic and Hypertensive patients. 3) known history of drug allergy. 4) Pregnant and lactating women. 5) Chronic respiratory and cardiovascular disease.

Design outcomes

Primary

Measure	Time frame
To study and compare the effects of intravenous lignocaine IV 2% (2mg/kg) with nebulization of 2% lignocaine (2 mg/kg) on hemodynamic response to laryngoscopy and endotracheal intubation.Timepoint: From shifting on OT table till 15 minutes post endotracheal intubation	—

Secondary

Measure	Time frame
To evaluate any side effects with use of this drug in both routesTimepoint: Baseline	—

Countries

India

Contacts

Public ContactSudarshan M B

Mysore Medical College and Research Institute

drmbs1975@yahoo.com9900262710

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026