Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Inj. Fentanyl 4 microgram/kg iv before intubation: To assess the efficacy and safety of 4 µg /kg of Inj.Fentanyl iv as premedication before 5 minutes
in attenuating hemodynamic stress
Sponsors
Goverment of Gujarat
Eligibility
Inclusion criteria
Inclusion criteria: Patients posted for elective surgery under general anaesthesia requiring endotracheal intubation. ASA physical status I and II BMI :18-30 kg/m2. Modified Mallampatti classification I & II
Exclusion criteria
Exclusion criteria: Patient refusing for consent. Patients with Diabetes, COPD, Renal disease, Valvular heart disease, AV conduction block, Aortic stenosis, Left ventricular failure etc. Patients on Medications (sedatives, opioids, anti-psychiatric drugs and ß blocker) Anticipated difficult intubation BMI =30kg/m2 Intubation attempt lasting longer than 20 seconds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters compared will be: Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP)Timepoint: Time frame will be Baseline measures , at the time of premedication , after induction , after laryngoscopy and intubation, 1 mins, 3 mins, 5 mins and 10 mins. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Intra operative : HR, SBP, DBP, MAP Timepoint: Time frame will be 20 mins , 30 mins, 40 mins , 50 mins, 60 mins;(2) Post operative complications: Sedation, Respiratory depression, chest wall rigidity, Bradycardia, Hypotension, Pruritus, Nausea, VomitingTimepoint: Time frame will be 20 mins , 30 mins, 40 mins , 50 mins, 60 mins | — |
Countries
India
Contacts
Public ContactDr Shakuntala J Goswami
B.J.Medical College and Civil Hospital Ahmedabad
Outcome results
None listed