Clinical and Radiographic Success of Root Canal Treatment for Milk Teeth after Using Laser or Antibiotic Paste as Canal Disinfectant

Clinico-Radiographic Evaluation and Anti-Microbial Efficacy of Chlorhexidine Solution (CHX), Modified Triple Antibiotic Paste (MTAP) and Diode Laser as Disinfectant in Mandibular Primary Molar Pulpectomy -A Randomized Clinical Study - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069389

Enrollment

Registered

2024-06-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases Health Condition 2: K047- Periapical abscess without sinus

Interventions

Intervention1: Diode Laser and Modified Triple Antibiotic Paste: Low wavelength diode laser (Biolase Laser) will be used in canal for 1 minute and tooth will be sealed for 7 days with temporary restor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients between 4 to 10 years having deciduous teeth with infected pulp. 2. Teeth with more than two-third of root length intact 3. Children having mandibular primary molars diagnosed with pulp necrosis, chronic irreversible pulpitis, physiologic root resorption equal to or less than one-third 4. Normal and healthy patients with no systemic disease. 5. Guardian who are willing to give a written informed consent and assent by children will be included in the study.

Exclusion criteria

Exclusion criteria: 1. Childrens those who have been administered antibiotics in the last three months before the date of reporting. 2. Teeth with pulp canal obliteration or internal or external pathological root resorption visible in periapical radiographs. 3. Teeth which are previously treated with pulpectomy procedures 4. Patients with cellulitis / space infection 5. Patients allergic to antibiotics used (Metronidazole, Ciprofloxacin, Clindamycin)

Design outcomes

Primary

Measure	Time frame
The results of the present study will provide the dental professionals, the better evidence for the choice of canal disinfectant. The results and their interpretation could be a valuable addition to the one already available in literature and help the clinicians gain a better root canal disinfection using CHX , MTAP and Laser.Timepoint: The outcome will be assessed at baseline, 6 months and 12 months	—

Measure

Time frame

The results of the present study will provide the dental professionals, the better evidence for the choice of canal disinfectant. The results and their interpretation could be a valuable addition to the one already available in literature and help the clinicians gain a better root canal disinfection using CHX , MTAP and Laser.Timepoint: The outcome will be assessed at baseline, 6 months and 12 months

—

Secondary

Measure	Time frame
The results of the present study will provide idea about duration to heal the lesion using different intracanal disinfection techniqueTimepoint: The outcome will be assessed at baseline, 6 months & 12 months	—

Countries

India

Contacts

Public ContactAnshula Deshpande

Sumandeep Vidyapeeth Deemed To Be University, Pipaliya, Vadodara

dranshula@gmail.com7600916400

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 27, 2026