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Evaluation of fluid overload in septic patients in intensive care unit

Evaluation of fluid overload in Septic patients admitted to intensive care unit with Combined Venous Excess Lung Ultrasound (VExLUS) Score - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/069384
Enrollment
93
Registered
2024-06-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B- Imaging

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosis of sepsis (consistent with surviving sepsis campaign guidelines 2021 and clinical indication to be admitted in ICU)

Exclusion criteria

Exclusion criteria: Patients in hemodialysis program Patients with previously known conditions that interfere with portal Doppler assessments, namely liver cirrhosis, or severe tricuspid regurgitation with structural heart disease. If any of these conditions are identified during the present episode, the patient would also be excluded. Age less than 18 years Patients subjected to withdrawal of care Hemodynamic instability due to active hemorrhage Acute coronary syndrome Indication for immediate surgery Received CPR within 24 hours of enrollment Pregnancy

Design outcomes

Primary

MeasureTime frame
Incidence of global fluid overload by measuring VExLUS scoreTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time

Secondary

MeasureTime frame
To asses correlation between VexLUS score and cumulative fluid balanceTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To asses correlation between VexLUS score and acute kidney injuryTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To asses correlation between VexLUS score and ICU length stayTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To asses correlation between VexLUS score and congestive respiratory failure(not attributed to other causes)Timepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;Proportion of the need for diuretic use or Renal Replacement therapy to correct fluid overloadTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To predict 28 day mortality on VexLUS scoreTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time

Countries

India

Contacts

Public ContactDr Ajeet Kumar

AIIMS Patna

ajeetanaes@gmail.com9312501413

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026