Health Condition 1: B- Imaging
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of sepsis (consistent with surviving sepsis campaign guidelines 2021 and clinical indication to be admitted in ICU)
Exclusion criteria
Exclusion criteria: Patients in hemodialysis program Patients with previously known conditions that interfere with portal Doppler assessments, namely liver cirrhosis, or severe tricuspid regurgitation with structural heart disease. If any of these conditions are identified during the present episode, the patient would also be excluded. Age less than 18 years Patients subjected to withdrawal of care Hemodynamic instability due to active hemorrhage Acute coronary syndrome Indication for immediate surgery Received CPR within 24 hours of enrollment Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of global fluid overload by measuring VExLUS scoreTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time | — |
Secondary
| Measure | Time frame |
|---|---|
| To asses correlation between VexLUS score and cumulative fluid balanceTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To asses correlation between VexLUS score and acute kidney injuryTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To asses correlation between VexLUS score and ICU length stayTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To asses correlation between VexLUS score and congestive respiratory failure(not attributed to other causes)Timepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;Proportion of the need for diuretic use or Renal Replacement therapy to correct fluid overloadTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time;To predict 28 day mortality on VexLUS scoreTimepoint: 0-12hrs 24-36hrs 48-72hrs Discharge time | — |
Countries
India
Contacts
AIIMS Patna