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A study to assess the difference of the partial pressure of CO2 between venous and arterial blood gas in children having septic shock

Assessment of the Peripheral venous to arterial pCO2 gap in Paediatric Septic Shock - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/069348
Enrollment
40
Registered
2024-06-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R578- Other shock

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Lok Nayak Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age group 1 month to 12 years presenting with septic shock as per the Phoenix Sepsis Criteria given by the International SCCM Paediatric Sepsis Definition Task Force in January 2024

Exclusion criteria

Exclusion criteria: 1) Patients who have received fluid boluses or inotropes before presenting in our Paediatrics department 2) Patients who are a known case of cyanotic heart disease and with a known right to left shunt lesion 3) Patients who are a known case of chronic lung disease and chronic kidney disease 4) Patients who are a known case of vasculitis and gangrene 5) Patients who are a known case of cytotoxic hypoxia

Design outcomes

Primary

MeasureTime frame
Change in peripheral venous to arterial pCO2 gapTimepoint: At 1 hour and 6 hours from 0 hour of treatment

Secondary

MeasureTime frame
Comparison of the proportion of patients having high peripheral venous to arterial pCO2 gap between patients achieving and not achieving shock reversalTimepoint: Within 6 hours of treatment;Comparison of the proportion of patients having high peripheral venous to arterial pCO2 gap between survivors and non survivorsTimepoint: At the time of discharge/death;Correlation of peripheral venous to arterial pCO2 gap and lactate clearanceTimepoint: At 1 hour and 6 hours of treatment;Proportion of patients having high peripheral venous to arterial pCO2 gapTimepoint: At 0 hour, 1 hour and 6 hours of treatment

Countries

India

Contacts

Public ContactHarshit Mittal

Maulana Azad Medical College

drvkumar1@gmail.com9313985662

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026