Health Condition 1: C508- Malignant neoplasm of overlappingsites of breast
Conditions
Interventions
None listed
Sponsors
JIPMER PUDUCHERRY
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women of age more than 18 years 2.Tumor stage T1, T2, T3, N0, N1 according to AJCC with no distant metastasis 3. Single clinical and mammographic lesion 4. Patients with residual disease following NACT and planned for BCS
Exclusion criteria
Exclusion criteria: 1. Tumor stage T4, N2 OR M1 according to the AJCC 8th edition 2. Presence of multifocal and multicentric lesion 3. Patients with complete clinical/radiological response to chemotherapy 4. Tumor to breast tissue ratio is very high 5. Recurrent breast carcinoma 6. Women with a strong family history of carcinoma of breast or BRCA1 and BRCA2 mutation carriers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the diagnostic utility of surgical margin obtained through gross examination in predicting margin negativity in patients undergoing breast conservative surgery- Margin of BCS specimen will be assessed intra-opTimepoint: Base line | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Re-excision rate 2. Margin negativity at re-excisionTimepoint: Base line | — |
Countries
India
Contacts
Public ContactShivareddy
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed