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Study on using inheritance characters test for medication in new schizophrenia patients in northern India to enhance treatment effectiveness

A study to evaluate the clinical effectiveness of multigenetic pharmacogenomics guided treatment in drug naive schizophrenics in northern Indian population an open label randomized controlled trial - nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069270
Enrollment
60
Registered
2024-06-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F209- Schizophrenia, unspecified

Interventions

Intervention1: Multigenetic pharmacogenomic antipsychotic panel test: Sixty patients will be randomly divided into two groups: group A will receive standard treatment according, and group B will recei

Sponsors

Dr Amrita Kumari Pandey
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ICD-10 or 11 criteria for schizophrenia 2.Positive and Negative Syndrome Scale (PANSS) more than 60 score 3.Patient or legally authorized representative willing to give informed consent 4.Two generations of the patient living in northern India 5.Schizophrenic patients who have not received any psychotropics

Exclusion criteria

Exclusion criteria: 1.Concurrent substance use disorders 2.Neurological conditions 3.Other comorbid axis I psychiatric diagnoses 4.Severe unstable organic illnesses 5.Not able to give consent 6.Pregnant or lactating females

Design outcomes

Primary

MeasureTime frame
The time course of schizophrenia severity which will be measured by the percentage PANSS score change from baseline and at the end of 3 monthTimepoint: 18 months

Secondary

MeasureTime frame
Response or remission rate will be calculated at each time point (1, 2, 3 months) using the PANSS score Early remission: change of 20 % in PANSS score Response: more than a 50 % change in PANSS Complete remission: less than 3 PANSS score Timepoint: 18 months

Countries

India

Contacts

Public ContactDR Farhan Ahmad Khan

Jawaharlal Nehru Medical College

dr.farhan.k@gmail.com9759468300

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026