Comparative study to evaluate the effect of Shuddha guggulu with and without virechan karma ( purgation therapy ) in patients of dyslipidimia.

Comparative clinical trial to evaluate the efficacy of shuddha guggulu with and without virechana karma in dyslipidemia - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069222

Enrollment

Registered

2024-06-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E789- Disorder of lipoprotein metabolism, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) Any one of the dearranged parameter of lipid profile ( Total cholesterol, Triglyceride, LDL, HDL, VLDL) 2) Patient of either sex of age between 20 â?? 65.

Exclusion criteria

Exclusion criteria: 1) Patients who are contraindicated for virechana karma- like lower GI bleeding, Prolapse of rectum, incontinence of stool, Pregnant and lactating women will not be included in the trial in group A. 2) CAD patients , patients on any ongoing medications that are likely to affect lipid levels. 3) Patients with renal or hepatic impairement (Sr creatinine greater than 1.8mg/dl, SGPOT greater than 200u/L, SGPT greater than 280uL). 4) Patients with co-morbid conditions such as Hypertension grade 2 ( greater than or equal to 160/100mm of Hg) or more, Diabetes Mellitus (having HbA1c greater than 7.5 percent with or without hyperglycemic medications 5) Patients who are on anti tubercular , anti retroviral and anti hyperlipidemic medications. 6) Patients requiring emergency treatment

Design outcomes

Primary

Measure	Time frame
Primary outcomes would be measured by lab investigation of extended lipid profile ( including total cholesterol, triglyceride, ldl, vldl, hdl, apolipoprotein A1 and apolipoprotein B) Timepoint: Primary outcomes would be measured by lab investigation of extended lipid profile ( including total cholesterol, triglyceride, ldl, vldl, hdl, apolipoprotein A1 and apolipoprotein B) On baseline 60 days ,i.e, after completion of trial	—

Measure

Time frame

Primary outcomes would be measured by lab investigation of extended lipid profile ( including total cholesterol, triglyceride, ldl, vldl, hdl, apolipoprotein A1 and apolipoprotein B) Timepoint: Primary outcomes would be measured by lab investigation of extended lipid profile ( including total cholesterol, triglyceride, ldl, vldl, hdl, apolipoprotein A1 and apolipoprotein B) On baseline 60 days ,i.e, after completion of trial

—

Secondary

Measure	Time frame
To asses the add on effect of virechana karma with Shuddha guggulu on Hs-CRP level. The proportion of patients showing improvement in the quality of life using the questionnaire of WHO-QOL Bref Scale. Timepoint: After 60 days ie. post completion of the intervention	—

Countries

India

Contacts

Public ContactDr Aniket Rajput

Ayurvedic and Unani Tibbia College and Hospital

manojshamkuwar@gmail.com9354925019

Outcome results