Treatment of horizontal bone loss in chronic periodontitis patients using bone graft and PRF

Evaluation of effectiveness of Non-Incised Papilla Surgical Approach in the treatment of horizontal bone defects using allogenic bone graft and injectable platelet rich fibrin with or without platelet rich fibrin membrane in patients with periodontitis: A randomized controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069193

Enrollment

Registered

2024-06-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: DFDBA and PRF membrane: DFDBA and i-PRF along with PRF memebrane will used in NIPSA teechnique, patient will be followed up till 9 months. Control Intervention1: DFDBA and i-PRF: DFDBA

Eligibility

Inclusion criteria

Inclusion criteria: grade b chronic periodontitis patients

Exclusion criteria

Exclusion criteria: pregnant or lactating and systematically unhealthy patients

Design outcomes

Primary

Measure	Time frame
Supralaveolar attachment gain, location of tip of papilla, width of keratinized tissue, pocket probing depth, relative attchment level, relative gingival recession, plaque index, gingival indexTimepoint: Supralaveolar attachment gain (baseline and 9 months), location of tip of papilla (baseline and 9 months), width of keratinized tissue (baseline and 9 months), pocket probing depth (baseline 3 months, 6 months and 9 months), relative attchment level (baseline 3 months, 6 months and 9 months), relative gingival recession (baseline 3 months, 6 months and 9 months), plaque index (baseline 3 months, 6 months and 9 months), gingival index (baseline 3 months, 6 months and 9 months)	—

Measure

Time frame

Supralaveolar attachment gain, location of tip of papilla, width of keratinized tissue, pocket probing depth, relative attchment level, relative gingival recession, plaque index, gingival indexTimepoint: Supralaveolar attachment gain (baseline and 9 months), location of tip of papilla (baseline and 9 months), width of keratinized tissue (baseline and 9 months), pocket probing depth (baseline 3 months, 6 months and 9 months), relative attchment level (baseline 3 months, 6 months and 9 months), relative gingival recession (baseline 3 months, 6 months and 9 months), plaque index (baseline 3 months, 6 months and 9 months), gingival index (baseline 3 months, 6 months and 9 months)

—

Secondary

Measure	Time frame
pocket probing depth, relative attchment level, relative gingival recession, plaque index, gingival indexTimepoint: baseline, 6 months and 9 months	—

Countries

India

Contacts

Public ContactDr Shruti Bhatnagar

Sharad Pawar Dental College

bhatnagarshruti9@gmail.com9822689401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 12, 2026