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Use of tumour infiltrating lymphocytes in the prognosis of oral squamous cell carcinoma

Tumour Infiltrating Lymphocytes (TIL) and its correlation with prognostic pathologic parameters in resectable Oral Squamous Cell Carcinoma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/069186
Enrollment
75
Registered
2024-06-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C049- Malignant neoplasm of floor of mouth, unspecified

Interventions

Control Intervention1: NIL: NIL

Sponsors

Datta Meghe Institute of Higher Education and Research (DMIHER)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Cases diagnosed as Oral Squamous Cell Carcinoma of all the three Broder’s grade on biopsy irrespective of gender and age. 2)The patients whose surgical specimen is resected and submitted for histopathological examination, to surgical pathology section of Department of Pathology, JNMC, irrespective of surgery type

Exclusion criteria

Exclusion criteria: 1) The patients with inadequate clinical records. 2) The patients undergoing resection surgery for recurrent tumours of Squamous Cell Carcinoma. 3) Patients who receive pre-operative chemotherapy or any other monoclonal antibody treatment.

Design outcomes

Primary

MeasureTime frame
The immune profiling of tumour infiltrating lymphoid cells identified by expression of CD8, CD4 and CD57 in the tumour parenchyma and its border.Timepoint: 2 years—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Saoni Debroy

Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (DMIHER)

aravani@rediffmail.com9822684255

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026