A research study comparing pain relief effectiveness between two drugs nalbuphine versus ketamine used along with levobupivacaine in subcostal transversus abdominis plane block during laparoscopic cholecystectomy.

Comparison of analgesic efficacy between Nalbuphine versus Ketamine as an adjunct to Levobupivacaine in USG guided Subcostal Transversus Abdominis Plane block in Laparoscopic Cholecystectomy. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069184

Enrollment

Registered

2024-06-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: SUBCOSTAL TRANSVERSUS ABDOMINIS PLANE BLOCK: The enrolled patients will be randomly allocated via computer generated randomization into two groups. Patients will receive USG guided Subc

Eligibility

Inclusion criteria

Inclusion criteria: All patient of ASA grade 1 and 2 aged from 18-60 years with BMI of 18.5 to 29.9 kg/m2 who are undergoing elective Laparoscopic Cholecystectomy surgery will be included.

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Pregnancy 3. BMI above 30 kg/m2 4. Cerebrovascular disease 5. Systemic infection 6. Inability to understand the study protocol 7. Allergy to local anesthetics 8. Psychiatric condition that may affect patient evaluation 9. Coagulopathy 10. Intraoperative major events (cardiovascular, neurological) 11. Infection at site of injection 12. Any Hepatic disorder 13. Any Renal disorder

Design outcomes

Primary

Measure	Time frame
-To compare the duration of analgesia between the groups after administration of Subcostal TAP block. -To assess the time until 1st dose of rescue analgesia between the groups. -To quantify the amount of rescue analgesia required 24 hours post the administration of block. Timepoint: 24 hours	—

Secondary

Measure	Time frame
-To compare the hemodynamic parameters between the groups.Timepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr. Surendra Kumar Jangid

AIIMS Raebareli

dr.skjangid@gmail.com8560919243

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026