Health Condition 1: O295- Other complications of spinal andepidural anesthesia during pregnancy
Conditions
Interventions
Intervention1: Infusion of norepinephrine at 0.050mcg per min per kg body weight: 1 ampoule of 2 ml contains 4 mg norepinephrine tartrate equivalent to 2 mg noerepinephrine base(2:2). Take 2 such ampo
Sponsors
All India Institute of Medical Sciences, Bihar
Eligibility
Inclusion criteria
Inclusion criteria: Labouring and non-labouring pregnant women with period of gestation more than 37 weeks undergoing category II caesarean section. Non-reassuring cardiotocography (CTG) including anyone of the following- Fetal heart rate(FHR) as per RCOG guidelines (FHR 100-109bpm or 161-180bpm). Variability less than 5bpm for more than 40minutes but less than 90 minutes. Early deceleration. Variable deceleration. Single prolonged deceleration less than 90 seconds
Exclusion criteria
Exclusion criteria: Complications such as hypertensive disorders of pregnancy, cardiovascular or cerebrovascular disease, multiple gestation, known fetal abnormality. Hemodynamically unstable or baseline SBP less than 100 mmHg. ASA physical status 3 or more than 3. Severely compromised fetus who requires immediate administration of general anaesthesia. Presence of contra-indications for spinal anaesthesia. Participants who have received labour analgesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess frequency of post-spinal hypotension, intra-operative bradycardia, intra-operative hypertension.Timepoint: maternal heart rate and blood pressure will be taken at 2 minute interval from before intrathecal injection until the delivery of the fetus. | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence of fetal acidosis APGAR score NICU admission Intra-operative nausea and vomiting Total number of norepinephrine boluses given Total dose of norepinephrine given Duration of NICU stay Time between skin incision and delivery of the foetusTimepoint: APGAR score at 1 minute and 5 minute NICU admission within 24 hours of delivery | — |
Countries
India
Contacts
Public ContactDr Chandni Sinha
AIIMS PATNA
Outcome results
None listed