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Comparision of prophylactic infusion of Phenylephrine versus Norepinephrine for the prevention of post spinal hypotension in parturients undergoing elective caesaeran section-A double blinded,randomised controlled trial

Comparision of prophylactic infusion of Phenylephrine versus Norepinephrine for the prevention of post spinal hypotension in parturients undergoing elective caesaeran section-A double blinded, non inferiority, randomised controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069129
Enrollment
80
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O748- Other complications of anesthesiaduring labor and delivery

Interventions

Intervention1: Paturients undergoing Elective caesarean section: Patients will be fasted overnight and will given IV metoclopramide 10 mg and Pantoprazole 40 mg iv.On arrival to the operating room ,

Sponsors

Department of Anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologist grade Non labouring,normotensive parturients Term singleton pregnancy Posted for Elective caesarean section under Spinal anaesthesia

Exclusion criteria

Exclusion criteria: Known fetal abnormality, Pre existing or pregnancy-induced hypertension, Known cardiovascular or cerebrovascular disease, Allergy or hypersensitivity to study drugs Thrombocytopenia, coagulopathy, or any medical contraindication to spinal anaesthesia Weight-50-100kg Height-140 or 180cm Patients who refused to give consent

Design outcomes

Primary

MeasureTime frame
To measure proportion of hypotension between 2 groupsTimepoint: 1 hour

Secondary

MeasureTime frame
Secondary objectives - incidence of maternal bradycardia, nausea and vomiting, reactive hypertension, requirement of rescue boluses of vasopressor and atropine between the 2 groups.Timepoint: 1 hour

Countries

India

Contacts

Public ContactDr Rachana R

S.Nijalingappa Medical College

anilganesh22@gmail.com9964526598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026