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An observational study to determine haemodynamic stability and renal outcomes in patients undergoing renal transplantation under either BIS monitored Propofol based Total Intravenous Anaesthesia (TIVA) or MAC monitored Sevoflurane based inhalational anaesthesia

An observational study to determine haemodynamic stability and renal outcomes in patients undergoing renal transplantation under either Bispectral Index (BIS) monitored Propofol based Total Intravenous Anaesthesia (TIVA) or Minimum Alveolar Concentration (MAC) monitored Sevoflurane based inhalational anaesthesia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/069128
Enrollment
96
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z940- Kidney transplant status

Interventions

Intervention1: Not Applicable: Not aplicable Control Intervention1: Not Applicable: NIL

Sponsors

Apollo Multispeciality Hositals Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a. Patient visiting the Nephrology and renal Transplant Unit of Apollo Multispeciality Hospitals Limited. b. Patients undergoing renal transplantation. c. Patients from 18 years to 75 years of age group of either sex will be included. d. The patients/patients’ caregivers who will give the written consent to participate in the study.

Exclusion criteria

Exclusion criteria: a. Renal Transplant recipients with Significant Cardiac disease (Ejection Fraction (EF) less than 40 percent) b. Renal disease with a significant potential for recurrence and early kidney graft loss. c. Patients of age less than 18 years and greater than 75 years will be excluded. d. The patients/patients caregivers who will not give the written consent to participate in the study

Design outcomes

Primary

MeasureTime frame
i. To determine intra-op hemodynamic [Heart Rate (HR), Mean Arterial pressure (MAP), Pulse pressure variation (PPV)] stability by observing every 10 minutes and recovery time, which is the time to awakening at the end of surgery.Timepoint: 2 hours 40 minutes

Secondary

MeasureTime frame
i. To determine post-operative Haemodynamics, Urine Output, O2 requirement & Sensorium for 48 hours ii. To determine Magnesium (Mg), Calcium (Ca) & Trajectory for Creatinine from 48 hours till 7 daysTimepoint: 7 Days

Countries

India

Contacts

Public ContactDr Saikat Sengupta

Apollo Multispeciality Hospitals Ltd

saikatsg@gmail.com9830179539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026