Health Condition 1: I169- Hypertensive crisis, unspecified
Conditions
Interventions
Intervention1: Intravenous Labetalol: Labetalol 20 mg given as stat dose, followed by incremental doses of 20–80 mg every 10 minute until the target BP goal is achieved. Maximum dose of labetalol will
Sponsors
KPC Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.SBP =180 mm Hg / DBP =120 mm Hg with evidence of acute end organ damage 2.Patient above 18 years of age. 3.Patient / legally acceptable representative of the patient who are willing to provide informed written consent.
Exclusion criteria
Exclusion criteria: COPD, Bradycardia , Pregnancy ,LVEF less than 35% , recent use of any intravenous beta blockers or antihypertensives or phosphodiesterase inhibitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients achieving the target MABP (reduction of the MABP by 25% from the original MABP at presentation) in the groups receiving GTN and LabetalolTimepoint: At baseline , 1 hour, 2 hours and 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic and Diastolic blood pressureTimepoint: 30 mins,1hour, 2 hours, 6 hours, 12 hours, 24 hours | — |
Countries
India
Contacts
Public ContactABHIJIT KUMAR SINHA
KPC MEDICAL COLLEGE and HOSPITAL
Outcome results
None listed