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Evaluation of regenerative potential of 1.2 percent Rosuvastatin-loaded biodegradable membrane in the treatment of Mandibular furcation defect

Efficacy of 1.2 percentRosuvastatin coated GTR membrane in Mandibular grade Il furcation defect - nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069093
Enrollment
10
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Rosuvastatin loaded collagen membrane: Rosuvastatin is a member of statin drugs, a cholesterol lowering drug which an antibiotic effect also. This is done in 6 months of span. Control I

Sponsors

Dr Amit Rajabhau Pawar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with mandibular furcation defects. Willingness to participate and comply with study procedures. Generally good systemic health. Non-smokers or willing to abstain during the study. Provide written informed consent.

Exclusion criteria

Exclusion criteria: Systemic conditions affecting periodontal healing. Pregnancy or lactation. Known allergies or sensitivities to study materials. Current use of medications interacting with Rosuvastatin or periodontal healing. Uncontrolled periodontal disease or recent periodontal therapy. Recent dental procedures in furcation area. Heavy smoking or unwillingness to abstain. History of drug or alcohol abuse.

Design outcomes

Primary

MeasureTime frame
Horizontal probing depth Vertical probing depth Vertical Clinical attachment level Vertical defect depth from IOPA Horizontal defect depth from IOPA Timepoint: 3 and 6 months

Secondary

MeasureTime frame
Pocket probing depth Clinical attachment loss/gain Volume of defect from CBCTTimepoint: 3 and 6 months

Countries

India

Contacts

Public ContactDr Amit Rajabhau Pawar

Saveetha dental College and Hospital, Chennai.

Arvinar.sdc@saveetha.com09486442309

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026