Health Condition 1: J22- Unspecified acute lower respiratory infection
Conditions
Interventions
Intervention1: Changing HFNC flow rate: Patients admitted in adult intensive care unit in AIIMS, Jodhpur with Acute hypoxemic respiratory failure who are on HFNC and hemodynamically stable with PaO2/
Sponsors
All India Institute of Medical Sciences Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: All hemodynamically stable patients admitted in Adult Intensive Care Unit in AIIMS,Jodhpur with acute hypoxemic respiratory failure,on High Flow Nasal Cannula with PaO2/FiO2 less than 300 are included in the study.
Exclusion criteria
Exclusion criteria: 1)Patients with hypoxemic respiratory failure requiring intubation and ventillatory support as per the attending clinician. 2)Patients of chronic respiratory failure. 3)Patients with neuromuscular disorders affecting respiratory muscles and/or diaphragm. 4)Patients with major cardiac, hepatic or renal functions derangement. 5)Pregnant patients. 6)Tracheostomised patients. 7)All the conditions where HFNC is contraindicated like upper airway obstruction, central apnoea, blocked nasal passages or choanal atresia, trauma or surgery to nasopharynx , pneumothorax etc.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1)To compare incidence of desaturation requiring increase in FiO2. 2)To compare change in ROX index. 3)To compare change in Respiratory Rate, Heart Rate and Mean Arterial Pressure. Timepoint: After 1 hour of changing HFNC oxygen flow rate. | — |
Primary
| Measure | Time frame |
|---|---|
| To compare change in PO2,PCO2 and PaO2/FiO2 at the flow rates of 60 litres/minute and 30 litres/minute.Timepoint: After 1 hour of changing HFNC oxygen flow rate. | — |
Countries
India
Contacts
Public ContactDr. Pradeep Kumar Bhatia
All India Institute of Medical Sciences ,Jodhpur.
Outcome results
None listed