Comparative evaluation of decrease in corneal cell count in mature cataract following laser assisted cataract surgery in four quadrants as compared to full softening.

COMPARATIVE EVALUATION OF CORNEAL ENDOTHELIAL CELL LOSS IN GRADE 3 CATARACT FOLLOWING FEMTOSECOND LASER ASSISTED CATARCT SURGERY, FOUR QUADRANT VERSUS FULL SOFTENING:RANDOMISED CONTROLLED TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069054

Enrollment

Registered

2024-06-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Evaluation of corneal endothelial cell loss in grade 3 cataract following femtosecond laser assisted cataract surgery in four quadrants: After confirming patient fit for surgery patient

Eligibility

Inclusion criteria

Inclusion criteria: 1.IMSC Grade III nuclear sclerosis (LOCS) 2.Any gender 3.Pupil dilation (size more than6mm) 4.Visual acuity less than 6/12 5.No previous ocular surgery or disease affecting corneal endothelium.

Exclusion criteria

Exclusion criteria: 1. Pathology of corneal endothelium. 2. Patients with neck and back rigidity. 3. Advanced glaucoma 4. ACD less than 3MM 5. Complicated cataract.

Design outcomes

Primary

Measure	Time frame
To compare mean corneal endothelial cell loss by analysing decrease in endothelial count in absolute number per mm square using specular microscope both ,four quadrant versus full softening nuclear fragmentation.Timepoint: pre-op and post op day 1 day7 day 30 .	—

Secondary

Measure	Time frame
? To compare central corneal thickness by analysing change in corneal thickness in microns using specular microscope pre and post operatively in both the groups.Timepoint: pre-op and post op day 1 day7 day 30 .	—

Countries

India

Contacts

Public ContactDr. SK Choudhary

Northern Railway Central Hospital

SHAILENDERCHOUDHARY@REDIFFMAIL.COM9717630563

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026