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Study to find out the effect of the drug -dexmedetomidine as a premedication for induction of general anaesthesia with propofol.

A study on the effect of Dexmeditomidine on the volume and dose of Propofol required to achieve loss of consciousness using Propofol based Marsh model of target controlled infusion. - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069049
Enrollment
64
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: R299- Unspecified symptoms and signs involving the nervous and musculoskeletal systems

Interventions

Intervention1: Dexmedetomidine: Prior to the induction of anaesthesia ,1mcg/kg dexmedetomididne ,diluted upto 10 ml,is given intravenously over 10 minutes. Control Intervention1: normal saline: Prior

Sponsors

Jawaharhal Nehru Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients aged 18-60 years 2)American Society of Anaesthesiologists (ASA) class1-2

Exclusion criteria

Exclusion criteria: Physical status of ASA class III or more Those with any significant systemic disorders Those with uncontrolled hypertension and cerebrovascular disease Those with co-morbid diseases liver or renal diseases Allergy to the study drugs Pregnant females Preoperative bradycardia less than 55 beats per minute Patients with known history of difficult intubation

Design outcomes

Primary

MeasureTime frame
volume and dose of propofolTimepoint: when there is loss of eye lash reflex

Secondary

MeasureTime frame
1.To compare the time required to achieve unconsciousness in both the groups. 2.To study the haemodynamic changes in both the groups Timepoint: when loss of eyelash reflex is noted

Countries

India

Contacts

Public ContactDr Neeraja K R

Jawaharlal Nehru Medical College

obaidahmad2008@gmail.com9897695761

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026