Comparison of ketoprofen patch vs diclofenac patch for post operative analgesia in patients operated for Percutaneous Nephrolithotomy (PCNL) and to assess their effect on serum creatinine.

To Compare the Efficacy Of Diclofenac Patch vs Ketoprofen Patch As Post-operative Analgesia And Effect On Serum Creatinine In Patients Undergoing Percutaneous Nephrolithotomy (PCNL) - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069037

Enrollment

Registered

2024-06-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Diclofenac: Diclofenac transdermal Patch 100 MG for 48 hours Control Intervention1: Ketoprofen: Ketoprofen transdermal Patch 30 MG for 48 hours

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I or II fit patients. Patients aged between 18 and 60 years of age. Patients undergoing surgeries under spinal anesthesia. Hemodynamically stable patients with all routine investigations within normal limits and without any comorbidities. Written informed consent from the concerned patient.

Exclusion criteria

Exclusion criteria: Patients who are not willing to participate in the study. Patients with ASA grade III and above physical status. Patients who are aged less than 18 and more than 60 years of age. Patients who are posted for emergency procedures. Patients with known allergy to the study drugs. Patients who are obese. Patients who have psychiatric, coagulopathies, neurological, neuromuscular, or cardiovascular disease or impairment of hepatic or renal function. Patients with coagulopathies and contraindication to SA

Design outcomes

Primary

Measure	Time frame
To compare the Efficacy of Diclofenac patch vs Ketoprofen patch- As Post-op Analgesia and effect on serum creatinine in Patients Undergoing PCNL.Timepoint: To assess the VAS score at 0,4,8,12,16, 24 and 48 hours Post operatively	—

Secondary

Measure	Time frame
To compare the Efficacy of Diclofenac patch vs Ketoprofen patch on serum creatinine in Patients Undergoing PCNL.Timepoint: Post operatively after 24 hours serum creatinine will be repeated.	—

Countries

India

Contacts

Public ContactDr Sandip Baheti

Dr. D. Y. Patil Medical College, Hospital And Research Centre, Pimpri, Pune

sandipbaheti1@gmail.com9822014401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026