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Clinical study to compare Enamel Matrix Derivative and Connective Tissue graft for correction of black triangles between teeth

Efficacy of Enamel Matrix Derivative compared with Connective Tissue Graft using Minimally invasive surgical techniques in the treatment of shallow gingival recessions with black triangles- A double blinded randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069032
Enrollment
20
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K060- Gingival recession

Interventions

Intervention1: Enamel Matrix Derivative: It consist of sterilized and lyophilized amelogenin fraction of porcine enamel matrix which is dissolved in propylene glycol alginate Control Intervention1: Co

Sponsors

Dr Harikumar K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Buccal recession depth less than or equal to 3mm in the maxilla with associated papillary recession 2 patients maintaining good oral hygiene after phase 1 therapy

Exclusion criteria

Exclusion criteria: 1 smokers 2 thin gingival biotypes 3 pregnant and lactating patients 4 patients with systemic disorders 5 patients who are under antibiotic or anti inflammatory therapy 6 patients with prosthetic crowns and restorations in the area of interest 7 non carious cervical lesions in the surgical site

Design outcomes

Primary

MeasureTime frame
1 Gingival embrasure fill 2 Papillary heightTimepoint: baseline 1 month 3months 6months 1 year

Secondary

MeasureTime frame
1 recession depth reduction 2 Keratinized tissue width 3 Keratinized tissue thickness 4 Complete root coverage 5 Mean root coverage 6 Bleeding on probing 7 Root coverage esthetic score Timepoint: baseline 1 month 3months 6months 1 year

Countries

India

Contacts

Public ContactDr Harikumar K

Kerala University of Health Sciences

harisindhu@hotmail.com9847128617

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026