Reduction of bacteria at various stages of root canal failure or retreatment cases after use of three different intracanal medicaments: calcium hydroxide, calcium hydroxide with chlorhexidine and calcium hydroxide with chitosan

Evaluation of microbial flora reduction at stages of endodontic retreatment after use of three different intracanal medicament : calcium hydroxide, calcium hydroxide with chlorhexidine and calcium hydroxide with chitosan - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/069029

Enrollment

Registered

2024-06-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: calcium hydroxide with chitosan, calcium hyrdoxide with chlorhexidine: to check bacterial reduction after giving three intracanal medicament and to check its effectivenss after placing

Eligibility

Inclusion criteria

Inclusion criteria: Single rooted or multi rooted teeth indicated for root canal retreatment as assessed with clinical and radiological signs ( PAI score 1-4). Clinical signs in patients without periapical radiolucency such as pain on palpation, discomfort to percussion, and persistent sinus tract. Root canal treatment completed for more than 2 years.

Exclusion criteria

Exclusion criteria: Tooth with advanced mobility Intracanal posts Radicular fractures Patients reporting with systemic disease starting with ASA Grade 3. Subjects with history of antibiotic treatment usage in the last 3 months.

Design outcomes

Primary

Measure	Time frame
1.Reduction in microbial load after placing an intracanal medicament. 2.Periapical healing. Timepoint: 1,3,6,12 months	—

Secondary

Measure	Time frame
postoperative pain & periapical healing will be assessed as the secondary outcome during course of studyTimepoint: 1 month,3 month,6 month,12 months,18 months	—

Countries

India

Contacts

Public ContactDr. ISHA TIWARI

Institute of Dental Sciences

shashirekhag@soa.ac.in9359468539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026