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Evaluating the effect of a new root canal Irrigant in retreatment cases.

Evaluating Antimicrobial Efficacy Of Silver Diamine Fluoride As Final Irrigant In Secondary Endodontic Infection: A Double Blinded Randomised Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069021
Enrollment
54
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 3.8% Silver Diamine Fluoride: 5ml of Silver Diamine Fluoride (3.8%) once in intracanal by side vented needle 2mm short of working lenght for 5min at baseline Control Intervention1: Sodi

Sponsors

Dr Vini Chohan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Previously single rooted filled teeth showing radiographic evidence of apical periodontitis or Failure of root canal treatment will be determined based on: 1.CLINICAL EXAMINATIONS Persistent symptoms Pain on palpation Discomfort to percussion Persistent sinus tract 2. RADIOGRAPHIC EXAMINATION PAI Score 1-4 Voids in & around the root canal filling

Exclusion criteria

Exclusion criteria: Antibiotic treatment in last 3 months Subjects with systemic disease starting with American society of Anaesthesiologist Grade 3 Subjects having teeth that cannot be isolated with a rubber dam, teeth with absence of coronary sealing, or teeth with periodontal pocket deeper than 3mm.

Design outcomes

Primary

MeasureTime frame
Assessment of Over all Microbial load reduction at various stages of endodontic retreatment using CFU analysisTimepoint: baseline, 1week

Secondary

MeasureTime frame
Quantification & comparing of E. faecalis bacterial load count using RT PCR analysisTimepoint: baseline, 1 week

Countries

India

Contacts

Public ContactDr Sonali Taneja

ITS CDSR, Muradnagar

sonalitaneja@its.edu.in9891688100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026