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The effects of Topical Insulin on Dry eye disease in Type 2 Diabetic patients

The effects of Topical Insulin on Dry eye disease in Type 2 Diabetic patients -A Randomised Control Trial - NIL

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/069019
Enrollment
130
Registered
2024-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Topical Insulin eye drops: Insulin eye drops in concentration of 25U/ml 1 drop instilled in both eyes 4 times a day for 8 weeks Control Intervention1: Eye drop polyethylene glycol 400 p

Sponsors

Dr Ritika Goel
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Type 2 Diabetes mellitus Age above 30years Baseline OSDI score more than 14

Exclusion criteria

Exclusion criteria: Sjogren syndrome Already Instilling any eye drops Use of contact lens History of ocular Trauma/ chemical injury / ocular surgery On systemic insulin

Design outcomes

Primary

MeasureTime frame
Compare OSDI score and dry eye parameters before and after use of topical insulinTimepoint: Topical insulin given for 8 weeks four times a day and the parameters will be assessed at baseline, 4 weeks and at 8 weeks

Secondary

MeasureTime frame
Compare OSDI score & dry eye parameters in topical insulin & artificial tear substitute groupTimepoint: Artificial tears given for 8 weeks four times a day & parameters will be assessed at baseline, 4 weeks at 8 weeks. The results will be compared with topical insulin

Countries

India

Contacts

Public ContactProfessor Adeeb Alam khan

Institute of Ophthalmology Jawaharlal Nehru Medical College and Hospital

9114ritika@gmail.com9119033990

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026