To Comparing the effectiveness of intravenous Dexmedetomidine and intravenous dexamethasone for the prevention of nausea and vomiting in postoperative period in patients undergoing gynaecological laparoscopic surgery

Comparative efficacy of intravenous dexmedetomidine and intravenous dexamethasone on the incidence of postoperative nausea and vomiting in patients undergoing gynaecological laparoscopic surgery - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068928

Enrollment

Registered

2024-06-14

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N00-N99- Diseases of the genitourinary system Health Condition 2: N809- Endometriosis, unspecified Health Condition 3: N739- Female pelvic inflammatory disease, unspecified Health Condition 4: N72- Inflammatory disease of cervix uteri Health Condition 5: N839- Noninflammatory disorder of ovary,fallopian tube and broad ligament, unspecified Health Condition 6: N888- Other specified noninflammatory disorders of cervix uteri

Interventions

Intervention1: Dexmedetomidine: Patient undergoing gynaecological laparoscopic surgery will be given single dose of intravenous dexmedetomidine (1mcg/kg) bolus before induction and will be assessed f

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 18-65 years with American society of Anesthesiologist I and II undergoing gynaecological laparoscopic surgery.

Exclusion criteria

Exclusion criteria: 1.patients with a known history of Gastric esophageal Reflux Disease 2.Allergic to study drugs 3.Body mass index =30kg/m2

Design outcomes

Primary

Measure	Time frame
To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeriesTimepoint: To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries	—

Measure

Time frame

To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeriesTimepoint: To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries

—

Secondary

Measure	Time frame
Intraoperative hemodynamic parameterTimepoint: Intraoperatively every 5 mins vital parameters will be assessed;Postoperative painTimepoint: Postoperatively using visual analog scale;Sedation scoreTimepoint: Postoperatively using Ramsay sedation score;To compare the postoperative nausea and vomiting score using visual analog scaleTimepoint: 0 hr, 4 hrs,12hrs	—

Countries

India

Contacts

Public ContactDr Dharam Singh Meena

Vardhman Mahavir Medical College and Safdarjung Hospital

dharams_meena@yahoo.com9910277131

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026