Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nebulization with Dexmedetomidine: Ultrasonic nebulization of 0.5mcg/kg dexmedetomidine diluted in volume of 4 ml
Intervention2: Nebulization with Magnesium sulphate: Ultrasonic nebuliz
Sponsors
All India Institute of Medical Sciences Patna
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing surgeries with tracheal intubation lasting for more than 1 hour and less than 2 hours ASA PS I and II Adult normotensive patients
Exclusion criteria
Exclusion criteria: Patient refusal Patients allergic to any of the study drugs Patient with any upper respiratory tract infection Patients with anticipated difficult intubation ASA PS III and IV (Uncontrolled Diabetes) Patients requiring more than 15 seconds of intubation Two attempts of laryngoscopy or more
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the incidence of Post Operative Sore throat within 24 hours of tracheal extubation. Timepoint: 0 hour 30 minutes 4 hours 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To find out any difference in systolic, diastolic & Mean arterial Blood pressure changes from baseline. Timepoint: 0 minutes of intubation 2 minutes of intubation 4 minutes of intubation 6 minutes of intubation;To measure the severity of Post Operative Sore throat (Moderate & Severe) by using a standard scoring system. Timepoint: 0 hour 30 minutes 4 hours 24 hours;To note any other laryngeal complications such as cough, or hoarseness of voice observed within 24 hours of tracheal extubation. Timepoint: 0 hour 30 minutes 4 hours 24 hours | — |
Countries
India
Contacts
Public ContactNeeraj Kumar
AIIMS Patna
Outcome results
None listed