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To see the response of intravenous fluid in patients who are having low blood pressure due to infection using echocardiography and bioreactance measured by Starling machine.

To compare the fluid responsiveness using transthoracic echocardiography and bio reactance in septic shock patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068907
Enrollment
56
Registered
2024-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

Intervention1: Bioreactance Device (Starling device): Bioreactance is potentially attractive since it only requires four electrodes stickers placed on the thorax. This technique is based upon the meas

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age greater than or equal to 18 years within 24 hours of ICU admission 2 Patients admitted with septic shock as per sepsis 3 definition and signs of tissue hypoperfusion i SBP less than 90 mmHg or decreased by greater than 40 mmHg ii hourly urine output less than 0.5ml per kg for more than 2 hrs iii HR greater than 100 per min iv skin mottling

Exclusion criteria

Exclusion criteria: 1 Patients less than 18 years of age and more than 80 years with any contraindication to PLR intracranial hypertension venous compression stocking intra abdominal hypertension 2 Pregnant patients 3 Severe anatomical abnormalities of aorta 4 Active arrythmias 5 Severe valvular heart disease 6 ECMO patients

Design outcomes

Primary

MeasureTime frame
To see if fluid responsiveness using bioreactance and transthoracic echocardiography is comparable or not in septic shock patientsTimepoint: 24 hours of diagnosis of septic shock

Secondary

MeasureTime frame
To compare cardiac output using bioreactance and transthoracic echocardiography in septic shock patientsTimepoint: 24 hours of diagnosis of septic shock

Countries

India

Contacts

Public ContactDr Anant Vikram Pachisia

Medanta, The Medicity, Gurgaon

anantndin@gmail.com9810368132

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026