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Effects of Morphine in cesarean sections when used with hyperbaric bupivacaine and levobupivacaine.

Comparison of effect of morphine as an adjuvant to hyperbaric bupivacaine and hyperbaric levobupivacaine in elective cesarean sections - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068901
Enrollment
60
Registered
2024-06-13
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Effect of adding morphine as an adjuvant to hyperbaric bupivacaine in elective cesarean sections: The patient will receive hyperbaric Inj Bupivacaine 0.5% 10 mg (1.9 ml) + Inj Morphine

Sponsors

Datta Meghe Institute of higher education and research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Female in the age group of 18-35 years. 2.Patient undergoing elective cesarean section. 3.Duration of Surgery 1-2 hours . 4.ASA 1 and 2 5.MPC 1 and 2 5.Weight of the patient more than equal to50 kilograms 8.Patients willing to participate in the study 9.Patient fulfilling criteria for Subarachnoid Block

Exclusion criteria

Exclusion criteria: 1.Lack of valid informed written consent 2.ASA grade 3 and 4 3.Weight of the patient less than equal to 50 kilograms 4.Infection at the Subarachnoid Block site 5.Patients with neurological and musculoskeletal disease 6.Patients with bleeding disorders 7.Patients on anticoagulants 8.History of allergy to local anaesthetic and injection Fentanyl.

Design outcomes

Primary

MeasureTime frame
To compare the hemodynamic and analgesic effects of morphine as an adjuvant to bupivacaine and levobupivacaine in patients undergoing elective cesarean section.Timepoint: 1 hours

Secondary

MeasureTime frame
1.Time to onset of sensory block and maximum level of sensory block reached. 2.The level of motor block . 3.Time to regression of two dermatomes of sensory block. 4.Duration of regression of sensory block level to T11 from maximum level . . 5.First rescue analgesia asked by patient ( VAS SCORE) 6.Neonatal outcomes (APGAR SCORE) 7.Any side effects. Timepoint: 3 hours

Countries

India

Contacts

Public ContactDr Angan Ghosh

Datta Meghe Institute of higher education and research Centre

drsusann02@rediffmail.com9921213404

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026