Health Condition 1: F41- Other anxiety disorders
Conditions
Interventions
Intervention1: Sertraline plus Vitamin D: Selective Serotonin Reuptake Inhibitor and Nutraceutical respectively. Tablet Sertraline will be started with 25mg/day which will be optimised between dose ra
Sponsors
Government Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with a primary diagnosis of Anxiety or fear related disorders as per ICD-11 (which includes patients diagnosed with Generalized Anxiety Disorder, Panic Disorder, Agoraphobia, Specific Phobia, Social Anxiety Disorder, Separation Anxiety Disorder, Selective Mutism, Other Specified Anxiety or Fear-Related Disorders). 2.Age group of 18-65yrs. 3.Any gender. 4.Vitamin D levels between 30nmol/L-75nmol/L. 5.Not on any psychotropic medication for current episode of illness 6.Patients having the capacity to give informed written consent as per section 4 of MHCA, 2017.
Exclusion criteria
Exclusion criteria: 1. Patients with an active substance use disorder within the past 6 months(in terms of fulfilling the ICD-11 criteria for substance dependence) except caffeine and nicotine. 2. Patients with any acute medical or surgical illness, anaemia, thyroid disoders. 3. Pregnant and lactating females. 4. Acutely violent patients or those having a current serious suicide risk. 5. Taking vitamins or dietary supplements containing vitamin D in last 3 months. 6. History of treatment resistance/poor response or major side-effects with SSRIs. 7. Having co-morbid diagnosis of intellectua ldisability, dementia, Alzeihmer"s disease, Parkinsons disease, Epilepsy. 8. Other co-morbid psychiatric illnesses including Schizophrenia, mood disorders, Obsessive compulsive and related disorder, disorders associated with stress (including PTSD and adjustment disorders), sleep disorders, eating disoders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the reduction in severity of anxiety in study group (receiving vitamin D plus standard of care (SOC)) & control group (receiving SOC only) as measured on 1. HAM-A 2. HDRS-17 3. CGI Timepoint: 0, 2, 4, 6, 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate vitamin D levels with severity of anxiety disorders.Timepoint: 0, 2, 4, 6, 8 weeks | — |
Countries
India
Contacts
Public ContactDr Prakrati Ratiya
Government Medical College and Hospital, Sector 32, Chandigarh
Outcome results
None listed