An observational study to evaluate the onset of effect of spinal anesthesia with addition of the drug Buprenorphine in the drug Ropivacaine 0.75% in lower abdominal surgeries and to study the duration of its effect during and after surgery

AN OBSERVATIONAL STUDY TO EVALUATE ONSET OF SENSORY AND MOTOR BLOCKADE AND DURATION OF SENSORY AND MOTOR BLOCKADE WITH HYPERBARIC ROPIVACAINE(0.75%) WITH BUPRENORPHINE AS AN ADJUVANTS FOR LOWER ABDOMINAL SURGERIES UNDER SPINAL ANAESTHESIA - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068792

Enrollment

150

Registered

2024-06-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Addition of Buprenorphine in Hyperbaric Ropivacaine 0.75% in spinal anesthesia for lower abdominal surgeries: 23 G Quincke’s spinal needle will be inserted. After confirmation of needle

Eligibility

Inclusion criteria

Inclusion criteria: Patients with physical status of ASA(American society of Anaesthesiologists) ASA I to ASA III, Patients undergoing above mentioned lower abdominal surgeries

Exclusion criteria

Exclusion criteria: Patients refusal to spinal anaesthesia, Infection at site of spinal needle insertion, Patients having allergy to local anesthetic drug or drug used in the study, Coagulopathy or bleeding disorder, Increased intracranial pressure, Patients having instrumentation at the site of spinal needle insertion

Design outcomes

Primary

Measure	Time frame
To assess the sensory and motor onset and duration of sensory and motor blockade of hyperbaric ropivacaine with buprenorphine in lower abdominal surgeries under spinal anaesthesiaTimepoint: 0 minutes, 10 minutes	—

Secondary

Measure	Time frame
To observe post operative time of rescue analgesia, time of first micturition and time of mobilisation after hyperbaric Ropivacaine with Buprenorphine in lower abdominal surgeries under spinal anaesthesiaTimepoint: From the time of completion of surgery till 24 hours	—

Countries

India

Contacts

Public ContactDr Akshita Patel

Shree Krishna Hospital, Pramukh Swami Medical College

vaibhavih@charutarhealth.org9909977446

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026