Effect of diaphragm function assessed by ultrasound in postoperative patients

Effect of dexmedetomidine propofol and midazolam on diaphragm function assessed by ultrasound in postoperative patients a randomised comparative study - Nil

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068761

Enrollment

126

Registered

2024-06-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: dexemeditomine Propofol infusion and midazolam infusion in postoperative period: dexemeditomine Propofol infusion and midazolam infusion in postoperative period Control Intervention

Eligibility

Inclusion criteria

Inclusion criteria: Who have undergone elective surgery under general anesthesia with endotracheal intubation expected to be extubated between next 12 - 72 hours ge18-60 years ASA physical status I or II male female

Exclusion criteria

Exclusion criteria: Patients who are hemodynamically unstable cardiothoracic surgery, Disease affecting diaphragm, for e.g.; myasthenia gravis, diaphragmatic hernia, cervical spine injury etc.

Design outcomes

Primary

Measure	Time frame
To compare differences in diaphragmatic excursion time index of postoperative patients on dexmedetomidine infusion, propofol infusion and midazolam infusion in postoperative periodTimepoint: To compare differences in diaphragmatic excursion time index of postoperative patients on dexmedetomidine infusion, propofol infusion and midazolam infusion in postoperative period 2 hrs to 24hrs	—

Secondary

Measure	Time frame
• To determine differences in following variables in postoperative patients on dexmedetomidine infusion, propofol infusion and midazolam infusion: – Diaphragm thickness fraction – Time gap between stopping of sedative drug and time of extubation – Richmond agitation sedation score (RASS) – Pain score- Behaviour Pain – Vital – HR, BP & SpO2- saturation – Side effect- like hypotension, bradycardia, patient ventilator desynchrony Timepoint: 2-24hrs	—

Measure

Time frame

• To determine differences in following variables in postoperative patients on dexmedetomidine infusion, propofol infusion and midazolam infusion: – Diaphragm thickness fraction – Time gap between stopping of sedative drug and time of extubation – Richmond agitation sedation score (RASS) – Pain score- Behaviour Pain – Vital – HR, BP & SpO2- saturation – Side effect- like hypotension, bradycardia, patient ventilator desynchrony Timepoint: 2-24hrs

—

Countries

India

Contacts

Public ContactProf GP Singh

King Georges Medical University Lucknow

gpsinghkgmu@gmail.com9415023076

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026