Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: iv diclofenac
: iv diclofenac Patients of this group will receive inj diclofenac sodium 75 mg in 100 ml NS as infusion over a period of 10 mins before induction of anesthesia and atracu
Sponsors
Sharda Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients scheduled for any elective surgery under general anesthesia with endotracheal intubation under succinylcholine. 2.ASA class I and II 3.Age 18-60 years 4.Both genders
Exclusion criteria
Exclusion criteria: 1. Patients already taking steroids, analgesics, antiemetic, and sedatives preoperatively for any clinical purpose. 2. Patients with past history of chronic pain. 3. Patients having history of endocrine, cardiovascular, renal or CNS disease. 4. Patients allergic to study drugs. 5. Contraindication of succinylcholine e.g. High potassium level, extensive burn or soft tissue injury. 6.BMI more than 30
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effects of premedication with two drugs (diclofenac vs ibuprofen) on succinylcholine induced postoperative myalgia in precurarized patients.Timepoint: 72 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| a) To observe and compare the grades of fasciculations. b) To compare the changes in the levels of serum creatinekinase c) To assess the relationship of fasciculations with serum creatinekinase and myalgia d) To compare the hemodynamic parameters (HR, SBP, DBP, MAP) perioperatively in four groups Timepoint: 72 hrs | — |
Countries
India
Contacts
Public ContactDr HIYA CHATUEVDI
School of Medical Sciences and Research
Outcome results
None listed