Health Condition 1: C170- Malignant neoplasm of duodenum Health Condition 2: C248- Malignant neoplasm of overlappingsites of biliary tract Health Condition 3: C258- Malignant neoplasm of overlappingsites of pancreas Health Condition 4: C259- Malignant neoplasm of pancreas, unspecified Health Condition 5: D490- Neoplasm of unspecified behavior of digestive system
Conditions
Interventions
Intervention1: NOT APPLICABLE: NOT APPLICABLE
Control Intervention1: NOT APPLICABLE: NOT APPLICABLE
Sponsors
Mahamana Pandit Madan Mohan Malaviya Cancer Centre
Eligibility
Inclusion criteria
Inclusion criteria: All consecutive patients undergoing pancreatoduodenectomy during the study period, with: 1. Age 18 to 80 years 2. ECOG less than 3 3. Patient undergoing pancreatoduodenectomy surgery for cancer involving duodenum, duodenal ampulla, bile duct, and head of pancreas.
Exclusion criteria
Exclusion criteria: 1. Patients who do not undergo complete resection and pancreatobiliaryenteric reconstruction. 2. Patients who are found to be metastatic on exploration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate and severity of postoperative complications esp. Clavein-Dindo (CD) classification, esp. CD =3 rates which includes POPF rates (postoperative pancreatic fistula), DGE rates (delayed gastric emptying), bile leak rates, postoperative hemorrhage rates, and re-exploration rates, SSI (surgical site infection) rates, pulmonary complications rate, cardiac complications rate, and renal complications rate.Timepoint: 30 days post surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day mortality Timepoint: 30 days post surgery;90- day mortality Timepoint: 90 days post surgery;Length of hospital stay/ ICU stay Timepoint: 90 days post surgery;Positive Intraop Bile culture and sensitivity. Timepoint: 30 days post surgery;Post neoadjuvant exploration rates Timepoint: 30 days post surgery;Postoperative histopathology stage and site of tumor, pathological diagnosis, Number of lymph nodes dissected, number of positive lymph nodes, lympho-vascular infiltration, perineural infiltration, perivascular infiltration, resection status (R0, R1, R2). Timepoint: 30 days post surgery;Presence and type of preoperative biliary drainage and interval between drainage and surgery. Timepoint: 30 days post surgery;Re-admission ratesTimepoint: 90 days post surgery | — |
Countries
India
Contacts
Public ContactDr Mayank Tripathi
Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Varanasi
Outcome results
None listed