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Effect of Eccentric Strengthening Exercise in patients with Knee Osteoarthritis : A Randomized Controlled Trial

Effect of Eccentric Strengthening Exercise in Knee Osteoarthritis - NIL

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068737
Enrollment
100
Registered
2024-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Eccentric Strengthening Exercise with Conventional Physiotherapy: Participants will begin each session with a 5-minute warm-up on a stationary cycle ergometer at low rate (50 rpm) & low
isometric strengthening exercise for 10 repetitions with 5 seconds hold × 1-2-3 sets on the quadriceps, and hip adductor muscle
mobilisation with movement for 6-10 repetitions × 3 sets
patellar glides at two to three oscillations/sec for 2 minutes in all directions as 3-6 repetitions
therapeutic ultrasound in continuous mode (1 watt/cm2 dose, 1 MHz) for 5 minutes and apply with a 5cm diameter applicator under the supervision of the physiotherapist. After receiving conventional car
eccentric hip abduction strengthening exercise for 10 repetitions × 3 sets by strapping sand bag to the ankle of the patient
weight will be distributed according to patient tolerance level and conditions
1-4 Session: 50% of 10 RM
5-8 Session: 75% of 10 RM
9-15 Session: 100% of 10 RM. Applicable for every exercise: 10s rest between each set & 20s rest between different modes of exercise & 5m rest between right & left knee exercise. Duration of treatment

Sponsors

Kazi Md Azman Hossain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i. Presence of Unilateral/Bilateral Knee osteoarthritis for at least six months, according to American College of Rheumatology criteria. ii. Tibiofemoral osteoarthritis-related knee pain and discomfort. iii. Capable of walking without the use of gait aids, and able to flex the knee beyond 90 degrees. iv. Anterior posterior bilateral standing radiograph presenting Kellgren and Lawrence Grade II/III Knee osteoarthritis. v. Providing consent of completion five week intervention and capable to carry with upon it. vi. Without suffering any unusual cardiac response during the six minute walk test.

Exclusion criteria

Exclusion criteria: i. Any knee surgery performed in the previous twelve months. ii. Lumbar radiculopathy, vascular claudication, severe anterior knee pain resulting from isolated patella femoral syndrome or chondromalacia in the knee, as well as further neurological, muscular, or joint conditions that could impair the function of the lower limbs. iii. Visible malformation of the knee, either varus or valgus. iv. Received hyaluronic acid or corticosteroid injections within three months of study enrollment; within two months, added new OTC or prescription painkillers. v. Pregnancy. vi. Mental or language obstacles limiting protocol implementation. vii. BMI over 30.

Design outcomes

Primary

MeasureTime frame
pain intensity, pressure pain threshold, strength, range of motion, and functional disability and depression severity of knee osteoarthritis patients.Timepoint: 6 months

Secondary

MeasureTime frame
Range of motion, and six-minutes walk test and depression severityTimepoint: 6 months

Countries

Bangladesh

Contacts

Public ContactDr Kazi Md. Amran Hossain

Jashore University of Science and Technology (JUST)

mz.hossain@just.edu.bd8801670962775

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026