Skip to content

How Changes in Body Chemistry during last days of Pregnancy Can Tell Us About Health Risks for Mother and Baby in High Blood Pressure Pregnancies

Metabolomic Perturbations of third trimester as predictors of maternal and neonatal outcomes in pregnancy-Induced Hypertension - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/068733
Enrollment
104
Registered
2024-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O099- Supervision of high risk pregnancy, unspecified

Interventions

Intervention1: Not applicable: Not applicable Control Intervention1: Not applicable: Not applicable

Sponsors

Geethika Yelleti
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pregnant women (aged 18 – 40 years) attending in their third trimester to KH OPD services and delivering at KH, Obstetrics and Gynaecology department, Manipal.

Exclusion criteria

Exclusion criteria: 1. Women not delivering at KH. 2. Women diagnosed with hypertension prior to pregnancy. 3. Known H/O cardiac disease, stroke or peripheral vascular disease. 4. History of preeclampsia due to premorbid thrombotic risk factors.

Design outcomes

Primary

MeasureTime frame
The study should identify specific metabolite patterns (signatures) in maternal serum, urine, and cord blood that are associated with HDPs.Timepoint: At the end of the study after patient recruitment.

Secondary

MeasureTime frame
The study should establish correlations between the identified metabolic signatures i.e, both adverse neonatal & maternal outcomes.Timepoint: In the end of the study;The study should provide insights into placental contributions to metabolic changes in HDPs.Timepoint: In the end of the study

Countries

India

Contacts

Public ContactDr Varashree BS

Kasturba Medical College

varashree.bs@manipal.edu9901729498

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026