Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: Topical Unani Formulation(homogenous powder as paste in water): Composition:Tukhm-i-panwad (Foetid cassia)Amla (Indian gooseberry) Laakh (Kerria lac insect) Zeera (cuminum cyminum)
Dos
Sponsors
National Research Institute Of Unani Medicine For Skin Disorders
Eligibility
Inclusion criteria
Inclusion criteria: 1 Participants of any gender in age group of 18-60 years 2 Participants of Qub ?(Tinea Corporis) having circumscribed lesions with any of the following signs and symptoms on body and limbs: a Presence of pruritus and burning b Presence of scales c Presence of central clearing d Erythematous papules 3 Participants with Positive KOH (10%) Smear Microscopy of Skin Scrapping from the active lesion for Dermatophytic hyphae Participants who are willing to participate and comply with the protocol and sign to IEC approved ICF.
Exclusion criteria
Exclusion criteria: The following patients will be excluded: Age below 18 years and above 60 years Patients with other form of tinea infection like tinea cruris (groin), tinea capitis (head), tinea pedis (foot), tinea mannum (hands), tinea unguium (nails), tinea barbae (beard), tinea faciei (face),etc. Patient with other concomitant diseases like psoriasis & eczema Patients who have received any topical antifungal therapy within last 2 weeks or oral antifungal therapy in the previous 4 weeks Patients with known active pulmonary/ cardiovascular/ liver/ renal or neurological diseases Known cases of Diabetes Mellitus or other immunocompromised disorders (HIV/ AIDS, etc.)/ Malignancies Patients with long-term history of steroid, cytotoxic and immunosuppressive therapy History of hypersensitivity to either itraconazole or any test drug Pregnant or lactating women, and women desiring pregnancy Participants not willing to give consent and to attend treatment schedule regularly
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Total Signs & Symptoms Score (TSSS) (Clinical Cure) 2. Conversion to Negative Mycology (Mycological Cure) Timepoint: TSSS At baseline 2nd, 4th and on 6th weeks. Mycological Cure at baseline and on 6th week. | — |
Secondary
| Measure | Time frame |
|---|---|
| DLQI (Dermatology Life Quality Index)Timepoint: At baseline 2nd, 4th and on 6th weeks. | — |
Countries
India
Contacts
Public ContactDr Madeeha Bano
National Research Institute Of Unani Medicine For Skin Disorders
Outcome results
None listed