A clinical trial on Poora Maathirai in the management of Uthiravatha suronitham (Rheumatoid Arthritis) among patients attending OPD and IPD of Government Siddha Medical College and Hospital, Palayamkottai

A Prospective, open labelled, single arm, non randomized, single centric, phase II, Clinical trail to determine the effectiveness of Poora Maathirai in the management of Uthiravatha suronitham (Rheumatoid arthritis) - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068638

Enrollment

Registered

2024-06-10

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M057- Rheumatoid arthritis with rheumatoid factor without organ or systems involvement

Interventions

Intervention1: Poora Maathirai: DOSAGE: 1 to 2 Tablets(Twice a day orally) Control Intervention1: NIL: NIL

Eligibility

Inclusion criteria

Inclusion criteria: 1.Pain and early morning stiffness 2.Those who are willing to participate in this study 3.RA factor test – positive 4.Anti CCP – positive 5.CRP above 20 mg/L 6.ESR elevated 7.ANA TEST in few selected cases

Exclusion criteria

Exclusion criteria: 1.Other degenerating joint diseases - osteoarthritis, sero negative spondylo arthritis, ankylosing spondylitis 2.Infectious joint diseases like, Tuberculosis, chronic poly arthritis in chickungunia viral infection. 3.Metabolic joint diseases like gout. 4.Patient who is on DMARD. (eg: methotrexate) 5.Pregnancy and lactating mother. 6.Chronic renal & liver disease patients

Design outcomes

Primary

Measure	Time frame
The outcome will be aimed at reducing the symptoms of Uthiravatha suronitham (Rheumatoid Arthiritis) and to determine the efficacy of Poora MaathiraiTimepoint: 48 days	—

Secondary

Measure	Time frame
1.To collect various Siddha literatures & modern journals for literature review on Uthiravatha suronitham. 2.To perform physicochemical, phytochemical, bio chemical analysis of Poora Maathirai. 3.To evaluate safety profile for acute & sub-acute toxicity of Poora Maathirai 4.To evaluate pharmacological activities of Poora Maathirai. 5.To study other cofactors related to disease like age, sex, dietary habits, family history, & socioeconomic status. 6.To study about the prevalence of Uthiravatha suronitham relation with diet & lifestyle. 7.To evaluate Siddha parameters (including Envagai thervu, Neerkuri-Neikuri) in Uthiravatha suronitham during trial period. 8.To evaluate dhegi of Uthiravatha suronitham patients. 9.To evaluate modern parametric changes in Uthiravatha suronitham. 10.To assess the quality of life of Uthiravatha suronitham patients. 11.To document Bio statistical analysis.Timepoint: 6 months	—

Measure

Time frame

1.To collect various Siddha literatures & modern journals for literature review on Uthiravatha suronitham. 2.To perform physicochemical, phytochemical, bio chemical analysis of Poora Maathirai. 3.To evaluate safety profile for acute & sub-acute toxicity of Poora Maathirai 4.To evaluate pharmacological activities of Poora Maathirai. 5.To study other cofactors related to disease like age, sex, dietary habits, family history, & socioeconomic status. 6.To study about the prevalence of Uthiravatha suronitham relation with diet & lifestyle. 7.To evaluate Siddha parameters (including Envagai thervu, Neerkuri-Neikuri) in Uthiravatha suronitham during trial period. 8.To evaluate dhegi of Uthiravatha suronitham patients. 9.To evaluate modern parametric changes in Uthiravatha suronitham. 10.To assess the quality of life of Uthiravatha suronitham patients. 11.To document Bio statistical analysis.Timepoint: 6 months

—

Countries

India

Contacts

Public ContactProf Dr T Komalavalli Alias Mehala

Government Siddha Medical College and Hospital palayamkottai

sukgsmc2014@gmail.com8072685509

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026