Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified
Conditions
Interventions
Intervention1: Intra cavitary brachytherapy applications of cervical cancer using a different fractionation schedule: 6Grays in 5 sessions using 2 applications. In the first application, 3 sessions of
Sponsors
Dr Muhammed Basil Y P
Eligibility
Inclusion criteria
Inclusion criteria: Biopsy-proven newly diagnosed carcinoma cervix Patients fit for chemotherapy Age less than 65 years without comorbid conditions FIGO Stage IB, IIA, IIB, IIIB without lower one-third involvement ECOG 0-2 No major life-threatening complications
Exclusion criteria
Exclusion criteria: More than 65 years ECOG 3 or more Prior pelvic radiotherapy Uncontrolled Diabetes and hypertension Patients with a prior history of DVT/Pulmonary embolism Lower one-third involvement of any stage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor Response in terms of partial or complete response. It will be assessed by clinical or radiological imaging.Timepoint: it will be assessed over 2 monthly follow up to 1 year. The baseline will be the initial tumor size before the application. | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute toxicities like diarrhea, dermatitis, anemia, neutropenia, etc.Timepoint: Assessed weekly during radiation therapy;Late toxicities which include cystitis & proctitis etcTimepoint: 6 months up to 1 year | — |
Countries
India
Contacts
Public ContactDr Parthasarathy V
Jawaharlal Institute of Post Graduate Medical Education and Research, JIPMER
Outcome results
None listed